Matthew Potthoff, PhD

Principal Investigator
Associate Professor of Pharmacology

Primary Office: 3322 PBDB
Office Phone: (319) 384-4438

Lab Office:  3310C PBDB
Lab Phone: (319) 335-7660
Email: matthew-potthoff@uiowa.edu

Matthew J. Potthoff graduated Summa Cum Laude from the University of Oklahoma in 2003 with a B.S. in Biology/Zoology. In 2007, he obtained his Ph.D. in Genetics and Development from the University of Texas Southwestern Medical Center in the laboratory of Dr. Eric N. Olson where he studied muscle development and metabolism. Between 2007-2012 he performed a Howard Hughes Medical Institute (HHMI) Postdoctoral Fellowship in the laboratories of Drs. David Mangelsdorf/Steven Kliewer and Dr. Shawn Burgess where he examined the role of endocrine fibroblast growth factors in regulating hepatic metabolism. In July 2012, Dr. Potthoff moved to the University of Iowa to become a member in the Department of Pharmacology and the F.O.E. Diabetes Research Center. His primary research interests are on the role of liver-derived factors, or hepatokines, in the regulation of systemic glucose and energy homeostasis. Matt’s hobbies include fishing, playing with the family, and throwing the ball with his dog, Cooper.

Faculty Profile
Diabetes Center Profile


Meghan Naber

Research Associate / Lab Manager
Address: 3320 PBDB
Phone: (319) 335-7660
Email: meghan-naber@uiowa.edu                                                                                                                                                                                                        

Originally from Spirit Lake, IA, Meghan received her BA in Biochemistry and Molecular Biology from Cornell College in Mount Vernon, IA and has worked in research at the University of Iowa since 2010. In her free time she enjoys true crime podcasts, paddle boarding, and baking. SSDGM.


Photo of Kristin Claflin
Kristin Claflin, PhD

Postdoctoral Scholar
Address: 3320 PBDB
Phone: (319) 335-7660
Email: kristin-claflin@uiowa.edu                                                                                                                                                                                                                                                                            

Kristin Claflin received her Ph.D. in Pharmacology from the University of Iowa in 2016, where she developed an interest in the neurobiology of energy homeostasis.  She has continued her training as a postdoc in the Department of Pharmacology studying how FGF21 regulates energy expenditure. Kristin enjoys spending time with her family, true crime podcasts and shopping at Target.


  Kyle Flippo, PhD

  Postdoctoral Scholar                      
  Address: 3320 PBDB
  Phone: (319) 335-7660
  Email: kyle-flippo@uiowa.edu                                                                                                                                                                                                            

Kyle received his B.S. in Biology at Aquinas College in 2010 and then began his graduate work in the lab of Dr. Stefan Strack in the Pharmacology Department at the University of Iowa. Kyle’s thesis work investigated how mitochondrial dynamics impact neuron survival and function. Kyle graduated with a Ph.D. in Pharmacology in 2017. In the Fall of 2017 Kyle started his current postdoctoral work in the Potthoff Lab focusing on defining neural circuits regulating metabolism and understanding how peripheral signals impact motivated behaviors. When not in the lab Kyle enjoys spending time with his wife and son, running, reading, hanging out with his dog Lana, woodworking, and fishing.


 
  Arvand Asghari, PhD

   Postdoctoral Scholar                      
   Address: 3320 PBDB
   Phone: (319) 335-7660
   Email: arvand-asgharikhonakdari@uiowa.edu                                                                                                                                                                                                   

Arvand received his bachelor and master’s degrees in Biotechnology from University of Tehran, Iran. In 2017, Arvand moved to Houston to pursue his PhD studies in cell and molecular biology at University of Houston, where he worked on the metabolism and regulatory effects of a cholesterol metabolite, 27-Hydroxycholesterol, on adipose tissue and obesity. Arvand graduated with a PhD in biology in 2021, and immediately joined Potthoff Lab as a postdoc. Arvand loves cooking and tasting new dishes, and he also enjoys traveling, camping, hiking, and podcasts on his spare times.


Photo of Sheps King
Abdul (Sheps) Qaadir King-Mcalpin

Graduate Student
Address:  3320 PBDB
Phone: (319) 335-7660
Email: abdulqaadir-king-mcalpin@uiowa.edu
Graduate Program: Molecular Medicine

Sheps earned his B.S. in 2013 at Morehouse College, Atlanta, Georgia. He completed a biology pre-med major and math minor at Morehouse before enrolling in the Medical Scientist Training Program here at University of Iowa. Sheps joined the Potthoff Lab fall of 2017.  Although he has a range of research interests, he is particularly enthusiastic about metabolism research since it correlates with his passion for exercise and its health benefits. Sheps enjoys lifting weights, cross training, biking, cooking, and traveling.


   Misty Perez

   Graduate Student
   Address:  3320 PBDB
   Phone: (319) 335-7660
   Email: misty-perez@uiowa.edu
   Graduate Program: Molecular Medicine

Misty earned her B.A. from Whittier College in 2020. She majored in biology and minored in chemistry before joining the Molecular Medicine program. Misty joined the Potthoff lab in early 2021 focusing on sweet-taste processing. Outside of lab, Misty likes coffee, cycling classes, and painting her nails. 


   Andrew Sullivan

   Graduate Student
   Address:  3320 PBDB
   Phone: (319) 335-7660
   Email: andrew-sullivan-1@uiowa.edu
   Graduate Program: Molecular Medicine

Andrew earned his B.A. in chemistry at St Olaf College in 2020 and enrolled in the Molecular Medicine Graduate Program here at the University of Iowa.  Andrew joined the Potthoff Lab early in 2021, focusing his efforts on tracking down the effect of FGF21 on energy expenditure, studying the neuronal pathways associated with the FTO locus, and working with single cell RNA sequencing datasets to generate hypotheses to explore with in vivo models. Outside of graduate work, Andrew spends his time skateboarding, buying and selling motorcycles, and boxing.


  Bolu Zhou

  Graduate Student
  Address:  3320 PBDB
  Phone: (319) 335-7660
  Email: bolu-zhou@uiowa.edu
  Graduate Program: Pharmacology

Bolu Zhou received her B.S. in pharmacy from Capital Medical University in China and later pursued a master’s in pharmacology from University of Vermont where she developed interest in pharmacology. Her hobbies include running weightlifting and cooking.


 
 Matthew Juber

   Graduate Student
   Address:  3320 PBDB
   Phone: (319) 335-7660
   Email: matthew-juber@uiowa.edu
   Graduate Program: Molecular Medicine

Matthew Juber received his B.S.e in Exercise Science and Health Promotion in 2018, and then his M.S. in Exercise Physiology at Florida Atlantic University in 2020 before entering the Molecular Medicine program. He joined the Potthoff lab in 2021 focusing on FGF21 intracellular signaling and the discovery of novel endocrine factors. Outside of the lab, Juber enjoys lifting weights, video games, recreational sports, and traveling with his girlfriend.


   Jesse Rose

   Graduate Student
   Address:  3320 PBDB
   Phone: (319) 335-7660
   Email: jesse-rose@uiowa.edu
   Graduate Program: Molecular Medicine

Jesse earned his M.A. in molecular biology from William Jewell College in 2020 and joined the Potthoff lab in the spring of 2021. Currently, he is investigating the effects of dietary manipulation on long term body weight control and the potential role of FGF21 as a therapy for fatty liver disease. Jesse also enjoys watching NFL football, playing pickle ball, and spending time with his wife.


   Kai Vorhies

   Graduate Student
   Address:  3320 PBDB
   Phone: (319) 335-7660
   Email: kai-vorhies@uiowa.edu
   Graduate Program: Molecular Medicine

Kai received his B.A. in Biology from Grinnell College in 2019, and joined the Potthoff lab in 2021. Kai is currently focused on the effects ketones have on brain signaling. Outside of lab, he enjoys swimming, biking, bathing, and cooking.